ISSN 1662-4009 (online)

ey0016.4-5 | New Therapeutic Options | ESPEYB16

4.5. The beneficial effect of combined GH/GnRHa therapy in increasing adult height outcome in children with ISS

L Lazar , S Levy , T Oron , J Meyerovitch , L de Vries , S Shalitin , A Tenenbaum , M Phillip , Y. Lebenthal

To read the full abstract: J Clin Endocrinol Metab. 2019;104:3287-3295.The current definition of idiopathic short stature (ISS) refers to a heterogeneous group of short children, in the absence of any underlying detectable cause, including both normal variants of growth and pathological conditions. ISS subjects have been reported to reach an average final height of −1.5 SDS in boys...

ey0015.9-3 | Late consequences of tumour therapy: prevention and monitoring | ESPEYB15

9.3 Growth and pubertal patterns in young survivors of childhood acute lymphoblastic leukemia

S Elitzur , R Houri-Shtrecher , M Yackobovitz-Gavan , G Avrahami , S Barzilai , G Gilad , Y Lebenthal , M Phillip , B Stark , I Yaniv , S Shalitin

To read the full abstract: J Pediatr Endocrinol Metab. 2017;30:869-877Several previous studies had focused on the early risk of metabolic syndrome or its components in survivors of childhood acute lymphoblastic leukaemia (ALL), while fewer data are available on pubertal development in these subjects. The merit of this study was to carefully investigate growth and pubertal development in a large ...

ey0015.10-16 | Psychology and quality of life | ESPEYB15

10.16 Factors associated with diabetes-specific health-related quality of life in youth with T1DM: the global TEENs study

BJ Anderson , LM Laffel , C Domenger , T Danne , M Phillip , C Mazza , R Hanas , S Waldron , RW Beck , F Calvi-Gries , C Mathieu

To read the full abstract: Diabetes Care. 2017;40:1002-1009Quality of life (QOL) measures have increasingly been considered as end-points of medical interventions. Both general QOL and health- and disease-specific quality of life can be assessed using well defined and validated questionnaires. The TEENs study is an international, cross-sectional study of youth with T1DM. 5,887 participants were follo...

ey0020.2-8 | Long-Acting Growth Hormone (LAGH) | ESPEYB20

2.8. Efficacy and safety of weekly somatrogon vs daily somatropin in children with growth hormone deficiency: A phase 3 study

CL Deal , J Steelman , E Vlachopapadopoulou , R Stawerska , LA Silverman , M Phillip , HS Kim , C Ko , O Malievskiy , JF Cara , CL Roland , CT Taylor , SR Valluri , MP Wajnrajch , A Pastrak , BS Miller

Brief summary: This 12-months randomized, controlled, phase 3 study compared the efficacy and safety of once-weekly Somatrogon 0.66 mg/kg/week with once-daily somatropin in prepubertal children with GHD. The efficacy of once-weekly Somatrogon was noninferior to once-daily somatropin, with similar safety and tolerability profiles.Somatrogon (MOD-4023) is a long-acting rhGH recently approved by the European Medicines Agency for the treatment of children wi...

ey0019.10-9 | Advances in clinical practice | ESPEYB19

10.9. Comparison of insulin dose adjustments made by artificial intelligence based decision support system and by physicians in people with type 1 diabetes using multiple daily injections therapy

R Nimri , A Tirosh , I Muller , Y Shtrit , I Kraljević , MM Alonso , T Milicic , B Saboo , A Deeb , A Christoforidis , Brinker M den , L Bozzetto , AM Bolla , M Krcma , RA Rabini , S Tabba , A Vazeou-Gerasimidi , G Maltoni , E Giani , I Dotan , IF Liberty , Y Toledano , O Kordonouri , N Bratina , K Dovc , T Biester , E Atlas , M Phillip

Diabetes Technol Ther. 2022;24:564-572. doi: https://pubmed.ncbi.nlm.nih.gov/35325567/Brief Summary: This physician survey-based study compared insulin dose recommendations between an artificial intelligence-based decision support system (ED-DSS) and 20 experienced physicians from 11 countries. Using data from 17 individuals with type 1 diabetes (T1D) treated with multiple daily insulin inj...

ey0015.10-10 | Continuous glucose monitoring, insulin pumps and artificial pancreas | ESPEYB15

10.10 International consensus on use of continuous glucose monitoring

T Danne , R Nimri , T Battelino , RM Bergenstal , KL Close , JH DeVries , S Garg , L Heinemann , I Hirsch , SA Amiel , R Beck , E Bosi , B Buckingham , C Cobelli , E Dassau , FJ Doyle , S Heller , R Hovorka , W Jia , T Jones , O Kordonouri , B Kovatchev , A Kowalski , L Laffel , D Maahs , HR Murphy , K Nørgaard , CG Parkin , E Renard , B Saboo , M Scharf , WV Tamborlane , SA Weinzimer , M Phillip

To read the full abstract: Diabetes Care. 2017;40:1631-1640[Comments on 10.9 and 10.10] These two publications describe guidelines made by the international learned societies on the use of continuous glucose monitoring devices. It is important to learn from these publications that education and guidance are pivotal before continuous glucose...